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Gene: ICAM1 (intercellular adhesion molecule 1) Homo sapiens
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Symbol: ICAM1
Name: intercellular adhesion molecule 1
Description: Exhibits integrin binding activity. Involved in several processes, including T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; cellular response to amyloid-beta; and negative regulation of apoptotic process. Localizes to the extracellular exosome. Implicated in several diseases, including Behcet's disease; Graves' disease; biliary atresia; eye disease (multiple); and inflammatory bowel disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); diabetes mellitus (multiple); hematologic cancer (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BB2; CD54; cell surface glycoprotein P3.58; human rhinovirus receptor; ICAM-1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; major group rhinovirus receptor; P3.58
Orthologs:
Mus musculus (house mouse) : Icam1 (intercellular adhesion molecule 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Icam1 (intercellular adhesion molecule 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Icam1 (intercellular adhesion molecule 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ICAM1 (intercellular adhesion molecule 1)
Canis lupus familiaris (dog) : ICAM1 (intercellular adhesion molecule 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Icam1 (intercellular adhesion molecule 1)
Sus scrofa (pig) : ICAM1 (intercellular adhesion molecule 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,271,120 - 10,286,615 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371910,380,707 - 10,397,291 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,242,779 - 10,258,291 (+)NCBINCBI36hg18NCBI36
Build 341910,242,778 - 10,258,291NCBI
Celera1910,276,917 - 10,292,687 (+)NCBI
Cytogenetic Map19p13.2NCBI
HuRef199,965,426 - 9,977,270 (+)NCBIHuRef
CHM1_11910,381,783 - 10,397,556 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
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Molecular Pathway Annotations
Phenotype Annotations
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References - uncurated

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