Gene: Cxcl2 (C-X-C motif chemokine ligand 2) Rattus norvegicus
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Symbol: Cxcl2
Name: C-X-C motif chemokine ligand 2
Description: Exhibits chemokine activity; involved in several processes, including cellular response to interleukin-1, cellular response to lipopolysaccharide, and neuron death; localizes to the extracellular space; biomarker of brain edema, intrahepatic cholestasis, lung disease (multiple), periodontitis, and pleurisy; orthologous to human CXCL2 (C-X-C motif chemokine ligand 2) and CXCL3 (C-X-C motif chemokine ligand 3); PARTICIPATES IN chemokine mediated signaling pathway; cytokine mediated signaling pathway; NOD-like receptor signaling pathway; INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1,2,4-trimethylbenzene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-X-C motif chemokine 2; chemokine (C-X-C motif) ligand 2; CINC-3; cytokine-induced neutrophil chemoattractant 3; macrophage inflammatory protein 2; Mip-2; MIP2; Scyb2; small inducible cytokine subfamily member 2; small inducible cytokine subfamily, member 2
Orthologs:
Homo sapiens (human) : CXCL2 (C-X-C motif chemokine ligand 2)  HGNC  Alliance
Mus musculus (house mouse) : Cxcl2 (chemokine (C-X-C motif) ligand 2)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL2 (C-X-C motif chemokine ligand 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01418,731,346 - 18,733,391 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01418,640,312 - 18,642,357 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41418,677,129 - 18,679,175 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11418,677,128 - 18,679,175 (-)NCBI
Celera1416,558,112 - 16,560,157 (-)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cxcl2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70069
Created: 2002-01-22
Species: Rattus norvegicus
Last Modified: 2019-04-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.