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Gene: ACOT8 (acyl-CoA thioesterase 8) Homo sapiens
Symbol: ACOT8
Name: acyl-CoA thioesterase 8
Description: Exhibits medium-chain acyl-CoA hydrolase activity and palmitoyl-CoA hydrolase activity. Involved in several processes, including acyl-CoA metabolic process; negative regulation of CD4 biosynthetic process; and peroxisome fission. Localizes to the peroxisomal matrix.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4,8-dimethylnonanoyl-coa thioesterase; acyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; choloyl-coenzyme A thioesterase; hACTE-III; hACTEIII; HIV-Nef associated acyl-CoA thioesterase; HIV-Nef-associated acyl-CoA thioesterase; HNAACTE; hTE; long-chain fatty-acyl-CoA hydrolase; NAP1; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; peroxisomal acyl-CoA thioesterase 2; peroxisomal acyl-coenzyme A thioester hydrolase 1; peroxisomal long-chain acyl-CoA thioesterase 1; PTE-1; PTE-2; PTE1; PTE2; thioesterase II; thioesterase III
Mus musculus (house mouse) : Acot8 (acyl-CoA thioesterase 8)  MGI  Alliance
Rattus norvegicus (Norway rat) : Acot8 (acyl-CoA thioesterase 8)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acot8 (acyl-CoA thioesterase 8)
Pan paniscus (bonobo/pygmy chimpanzee) : ACOT8 (acyl-CoA thioesterase 8)
Canis lupus familiaris (dog) : ACOT8 (acyl-CoA thioesterase 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acot8 (acyl-CoA thioesterase 8)
Sus scrofa (pig) : ACOT8 (acyl-CoA thioesterase 8)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh382045,841,721 - 45,857,405 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372044,470,360 - 44,486,048 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,903,768 - 43,919,442 (-)NCBINCBI36hg18NCBI36
Build 342043,903,767 - 43,919,442NCBI
Celera2041,180,856 - 41,196,530 (-)NCBI
Cytogenetic Map20q13.12NCBI
HuRef2041,212,129 - 41,227,770 (-)NCBIHuRef
CHM1_12044,373,492 - 44,389,180 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ACOT8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70372
Created: 2002-03-20
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.