Gene: Cdk2 (cyclin dependent kinase 2) Rattus norvegicus
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Symbol: Cdk2
Name: cyclin dependent kinase 2
Description: Exhibits cyclin binding activity and cyclin-dependent protein serine/threonine kinase activity; predicted to contribute to histone kinase activity; involved in several processes, including animal organ development, cellular response to insulin stimulus, and response to cAMP; localizes to the cytosol and nucleus; used to study membranoproliferative glomerulonephritis; orthologous to human CDK2 (cyclin dependent kinase 2); PARTICIPATES IN G1/S transition pathway; interleukin-2 signaling pathway; mTOR signaling pathway; INTERACTS WITH (+)-pilocarpine; (R)-mevalonic acid; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cell division protein kinase 2; cyclin dependent kinase 2-alpha; cyclin-dependent kinase 2
Orthologs:
Homo sapiens (human) : CDK2 (cyclin dependent kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Cdk2 (cyclin-dependent kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk2 (cyclin dependent kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK2 (cyclin dependent kinase 2)
Canis lupus familiaris (dog) : CDK2 (cyclin dependent kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk2 (cyclin dependent kinase 2)
Sus scrofa (pig) : CDK2 (cyclin dependent kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.073,124,953 - 3,132,533 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.073,097,653 - 3,105,210 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,000,196 - 2,007,682 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.172,000,196 - 2,007,682 (-)NCBI
Celera71,000,083 - 1,007,560 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdk2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70486
Created: 2002-05-02
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.