Gene: Tgfb2 (transforming growth factor, beta 2) Rattus norvegicus
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Symbol: Tgfb2
Name: transforming growth factor, beta 2
Description: Exhibits protein N-terminus binding activity, protein heterodimerization activity, and protein homodimerization activity; involved in several processes, including aging, animal organ development, and regulation of programmed cell death; localizes to several cellular components, including the basement membrane, cell surface, and cytoplasm; biomarker of diabetic neuropathy, myocardial infarction, and osteochondrodysplasia; orthologous to human TGFB2 (transforming growth factor beta 2); PARTICIPATES IN glypican signaling pathway; Hedgehog signaling pathway; transforming growth factor-beta Smad dependent signaling pathway; INTERACTS WITH (R)-lipoic acid; (R)-noradrenaline; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: TGF beta 2 protein; TGF-B2; TGF-beta-2; transforming growth factor beta-2; transforming growth factor beta-2 proprotein
Orthologs:
Homo sapiens (human) : TGFB2 (transforming growth factor beta 2)  HGNC  Alliance
Mus musculus (house mouse) : Tgfb2 (transforming growth factor, beta 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tgfb2 (transforming growth factor beta 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TGFB2 (transforming growth factor beta 2)
Canis lupus familiaris (dog) : TGFB2 (transforming growth factor beta 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tgfb2 (transforming growth factor beta 2)
Sus scrofa (pig) : TGFB2 (transforming growth factor beta 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013105,039,639 - 105,142,010 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013109,679,866 - 109,792,609 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413102,718,703 - 102,818,768 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113102,907,748 - 103,007,811 (-)NCBI
Celera1397,669,691 - 97,769,426 (-)NCBICelera
Cytogenetic Map13q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tgfb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70491
Created: 2002-05-02
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.