Gene: Nat2 (N-acetyltransferase 2) Rattus norvegicus
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Symbol: Nat2
Name: N-acetyltransferase 2
Description: Exhibits arylamine N-acetyltransferase activity; involved in several processes, including digestive tract development, response to hypoxia, and response to lipopolysaccharide; localizes to the cytosol; biomarker of end stage renal failure; orthologous to several human genes including NAT1 (N-acetyltransferase 1); PARTICIPATES IN caffeine pharmacokinetics pathway; caffeine metabolic pathway; INTERACTS WITH 4,4'-diaminodiphenylmethane; 4-aminobenzoic acid; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: arylamide acetylase 2; arylamine N-acetyltransferase 2; AT-2; N-acetyltransferase 2 (arylamine N-acetyltransferase); N-acetyltransferase type 2; N-Acetyltransferase-2 (arylamine N-acetyltransferase); NAT-2; Nat2a
Orthologs:
Homo sapiens (human) : NAT2 (N-acetyltransferase 2)  HGNC  Alliance
Mus musculus (house mouse) : Nat2 (N-acetyltransferase 2 (arylamine N-acetyltransferase))  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : NAT2 (N-acetyltransferase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Note: Loci in other organisms that are functionally homologous to this one are validly referred to as both NAT1 and NAT2; i.e., the functional homologs of NAT1 include mouse and rat Nat2, while the functional homologs of human NAT2 include mouse and rat Nat1. Name:sequence associations are consistent with current use in the field. [13 Feb 2013]
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01623,960,709 - 23,991,570 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01623,844,909 - 23,875,348 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41623,845,894 - 23,876,528 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11623,845,891 - 23,876,526 (-)NCBI
Celera1622,342,838 - 22,372,771 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Nat2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70492
Created: 2002-05-02
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.