Gene: Tert (telomerase reverse transcriptase) Rattus norvegicus
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Symbol: Tert
Name: telomerase reverse transcriptase
Description: Predicted to have several functions, including chaperone binding activity, nucleic acid binding activity, and nucleotidyltransferase activity; involved in several processes, including cellular response to hypoxia, negative regulation of cell death, and negative regulation of glial cell proliferation; localizes to the mitochondrion and nucleus; predicted to colocalize with the PML body; used to study chronic kidney disease and transient cerebral ischemia; biomarker of hepatocellular carcinoma and pulmonary hypertension; orthologous to human TERT (telomerase reverse transcriptase); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: telomerase catalytic subunit
Orthologs:
Homo sapiens (human) : TERT (telomerase reverse transcriptase)  HGNC  Alliance
Mus musculus (house mouse) : Tert (telomerase reverse transcriptase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tert (telomerase reverse transcriptase)
Pan paniscus (bonobo/pygmy chimpanzee) : TERT (telomerase reverse transcriptase)
Canis lupus familiaris (dog) : TERT (telomerase reverse transcriptase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tert (telomerase reverse transcriptase)
Sus scrofa (pig) : TERT (telomerase reverse transcriptase)
more info ...
Allele / Splice: Tertem2Mcwi  
Genetic Models: WKY-Tertem2Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0132,250,876 - 32,275,330 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0133,675,744 - 33,697,542 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4130,445,180 - 30,465,942 (-)NCBIRGSC3.4rn4RGSC3.4
Celera128,286,050 - 28,306,805 (-)NCBICelera
Cytogenetic Map1p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Tert
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70494
Created: 2002-05-02
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.