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Gene: Tfrc (transferrin receptor) Mus musculus
Symbol: Tfrc
Name: transferrin receptor
Description: Predicted to have several functions, including Hsp70 protein binding activity; chaperone binding activity; and protein homodimerization activity. Involved in several processes, including cellular response to leukemia inhibitory factor; positive regulation of bone resorption; and positive regulation of lymphocyte proliferation. Localizes to several cellular components, including HFE-transferrin receptor complex; endosome; and extracellular exosome. Human ortholog(s) of this gene implicated in breast carcinoma; multiple myeloma; ovarian cancer; and primary immunodeficiency disease. Is expressed in several structures, including alimentary system; extraembryonic component; liver; lung; and meninges. Orthologous to human TFRC (transferrin receptor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2610028K12Rik; AI195355; AI426448; AU015758; CD71; E430033M20Rik; mammary tumor virus receptor 1; Mtvr-1; Mtvr1; p90; TFR; TFR1; TR; transferrin receptor protein 1; Trfr
Homo sapiens (human) : TFRC (transferrin receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfrc (transferrin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfrc (transferrin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : TFRC (transferrin receptor)
Canis lupus familiaris (dog) : TFRC (transferrin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfrc (transferrin receptor)
Sus scrofa (pig) : TFRC (transferrin receptor)
Chlorocebus sabaeus (African green monkey) : TFRC (transferrin receptor)
Heterocephalus glaber (naked mole-rat) : Tfrc (transferrin receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1632,608,920 - 32,632,794 (+)EnsemblGRCm38mm10GRCm38
GRCm381632,608,896 - 32,632,794 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371632,608,982 - 32,632,880 (+)NCBIGRCm37mm9NCBIm37
MGSCv361632,528,768 - 32,552,537 (+)NCBImm8
Celera1633,088,313 - 33,112,331 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1623.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tfrc
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70503
Created: 2002-05-02
Species: Mus musculus
Last Modified: 2020-05-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.