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Gene: Tert (telomerase reverse transcriptase) Mus musculus
Symbol: Tert
Name: telomerase reverse transcriptase
Description: Exhibits telomerase RNA binding activity; telomerase activity; and transcription coactivator binding activity. Involved in several processes, including positive regulation of glucose import; positive regulation of hair cycle; and positive regulation of stem cell proliferation. Localizes to mitochondrion; plasma membrane; and telomerase catalytic core complex. Predicted to colocalize with PML body. Human ortholog(s) of this gene implicated in several diseases, including autosomal dominant dyskeratosis congenita 2; familial melanoma; hepatocellular carcinoma; idiopathic pulmonary fibrosis; and leukemia (multiple). Is expressed in several structures, including early conceptus; genitourinary system; hemolymphoid system gland; liver; and vibrissa follicle. Orthologous to human TERT (telomerase reverse transcriptase); PARTICIPATES IN hypoxia inducible factor pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; 4-hydroperoxycyclophosphamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EST2; MGC150124; TCS1; telomerase catalytic subunit; telomerase reverse transcriptase beta; TP2; TR; TRT
Homo sapiens (human) : TERT (telomerase reverse transcriptase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tert (telomerase reverse transcriptase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tert (telomerase reverse transcriptase)
Pan paniscus (bonobo/pygmy chimpanzee) : TERT (telomerase reverse transcriptase)
Canis lupus familiaris (dog) : TERT (telomerase reverse transcriptase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tert (telomerase reverse transcriptase)
Sus scrofa (pig) : TERT (telomerase reverse transcriptase)
Chlorocebus sabaeus (African green monkey) : TERT (telomerase reverse transcriptase)
Heterocephalus glaber (naked mole-rat) : Tert (telomerase reverse transcriptase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1373,626,911 - 73,649,843 (+)EnsemblGRCm38mm10GRCm38
GRCm381373,626,911 - 73,649,843 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371373,764,449 - 73,786,489 (+)NCBIGRCm37mm9NCBIm37
MGSCv361374,093,003 - 74,115,043 (+)NCBImm8
Celera1375,955,877 - 75,977,918 (+)NCBICelera
Cytogenetic Map13C1NCBI
cM Map1340.12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tert
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70505
Created: 2002-05-02
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.