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Gene: IGF1 (insulin like growth factor 1) Homo sapiens
Symbol: IGF1
Name: insulin like growth factor 1
Description: Exhibits signaling receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of cellular metabolic process; and positive regulation of signal transduction. Localizes to alphav-beta3 integrin-IGF-1-IGF1R complex and insulin-like growth factor ternary complex. Implicated in several diseases, including acne; brain ischemia; diabetes mellitus (multiple); myopia; and neurodegenerative disease (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); bone disease (multiple); diabetes mellitus (multiple); and eye disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IGF; IGF-I; IGF-IA; IGF-IB; IGF1A; IGFI; insulin-like growth factor 1; insulin-like growth factor 1 (somatomedin C); insulin-like growth factor I; insulin-like growth factor IA; insulin-like growth factor IB; mechano growth factor; MGF; somatomedin-C
Mus musculus (house mouse) : Igf1 (insulin-like growth factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Igf1 (insulin-like growth factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Igf1 (insulin like growth factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : IGF1 (insulin like growth factor 1)
Canis lupus familiaris (dog) : IGF1 (insulin like growth factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Igf1 (insulin like growth factor 1)
Sus scrofa (pig) : IGF1 (insulin like growth factor 1)
Chlorocebus sabaeus (African green monkey) : IGF1 (insulin like growth factor 1)
Heterocephalus glaber (naked mole-rat) : Igf1 (insulin like growth factor 1)
more info ...
Allele / Splice: See ClinVar data
Is Marker For: QTLs:   BW58_H   BW104_H  
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12102,395,874 - 102,481,744 (-)EnsemblGRCh38hg38GRCh38
GRCh3812102,395,860 - 102,481,839 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712102,789,645 - 102,875,563 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3612101,313,806 - 101,398,454 (-)NCBINCBI36hg18NCBI36
Build 3412101,292,143 - 101,376,791NCBI
Celera12102,453,601 - 102,538,345 (-)NCBI
Cytogenetic Map12q23.2NCBI
HuRef1299,849,028 - 99,933,911 (-)NCBIHuRef
CHM1_112102,756,305 - 102,841,149 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated