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Gene: Acsl3 (acyl-CoA synthetase long-chain family member 3) Rattus norvegicus
Symbol: Acsl3
Name: acyl-CoA synthetase long-chain family member 3
CRRD ID: 70552
Description: Exhibits arachidonate-CoA ligase activity and long-chain fatty acid-CoA ligase activity. Involved in several processes, including brain development; fatty acid metabolic process; and response to nutrient. Predicted to localize to several cellular components, including Golgi apparatus; lipid droplet; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in asthma; breast cancer; and prostate cancer. Orthologous to human ACSL3 (acyl-CoA synthetase long chain family member 3); PARTICIPATES IN fatty acid beta degradation pathway; eicosanoid signaling pathway via peroxisome proliferator-activated receptor gamma; fatty acid metabolic pathway; INTERACTS WITH 1-benzylpiperazine; 1-naphthyl isothiocyanate; 1-nitropropane.
Type: protein-coding
Also known as: Acs3; arachidonate--CoA ligase; brain acyl-CoA synthetase II; Facl3; fatty acid Coenzyme A ligase, long chain 3; LACS 3; long-chain acyl-CoA synthetase 3; long-chain-fatty-acid--CoA ligase 3
Homo sapiens (human) : ACSL3 (acyl-CoA synthetase long chain family member 3)  HGNC  Alliance
Mus musculus (house mouse) : Acsl3 (acyl-CoA synthetase long-chain family member 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Acsl3 (acyl-CoA synthetase long chain family member 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ACSL3 (acyl-CoA synthetase long chain family member 3)
Canis lupus familiaris (dog) : ACSL3 (acyl-CoA synthetase long chain family member 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Acsl3 (acyl-CoA synthetase long chain family member 3)
Sus scrofa (pig) : ACSL3 (acyl-CoA synthetase long chain family member 3)
Chlorocebus sabaeus (African green monkey) : ACSL3 (acyl-CoA synthetase long chain family member 3)
Heterocephalus glaber (naked mole-rat) : Acsl3 (acyl-CoA synthetase long chain family member 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0984,569,601 - 84,593,565 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl984,569,597 - 84,593,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0984,301,912 - 84,351,516 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4978,083,239 - 78,106,933 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1978,266,656 - 78,290,352 (+)NCBI
Celera977,647,726 - 77,671,370 (+)NCBICelera
Cytogenetic Map9q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Acsl3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70552
Created: 2002-05-20
Species: Rattus norvegicus
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.