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Gene: C5ar1 (complement C5a receptor 1) Rattus norvegicus
Symbol: C5ar1
Name: complement C5a receptor 1
CRRD ID: 70553
Description: Exhibits complement component C5a binding activity and complement component C5a receptor activity. Involved in several processes, including animal organ regeneration; negative regulation of neuron apoptotic process; and response to lipopolysaccharide. Localizes to cell surface and plasma membrane. Used to study adult respiratory distress syndrome; amyotrophic lateral sclerosis; neutropenia; obesity; and thrombosis. Biomarker of asthma and lung disease. Orthologous to several human genes including OPRPN (opiorphin prepropeptide); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane.
Type: protein-coding
Also known as: C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5aR; C5r1; complement C5a receptor; complement component 5, receptor 1; complement component 5a receptor 1
Homo sapiens (human) : C5AR1 (complement C5a receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : C5ar1 (complement component 5a receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C5ar1 (complement C5a receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : C5AR1 (complement C5a receptor 1)
Canis lupus familiaris (dog) : C5AR1 (complement C5a receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C5ar1 (complement C5a receptor 1)
Sus scrofa (pig) : C5AR1 (complement C5a receptor 1)
Chlorocebus sabaeus (African green monkey) : C5AR1 (complement C5a receptor 1)
Heterocephalus glaber (naked mole-rat) : C5ar1 (complement C5a receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0178,186,777 - 78,195,132 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl178,186,776 - 78,195,328 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,452,051 - 79,458,856 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera171,439,044 - 71,449,243 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on C5ar1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70553
Created: 2002-05-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.