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Gene: C5ar1 (complement C5a receptor 1) Rattus norvegicus
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Symbol: C5ar1
Name: complement C5a receptor 1
Description: Exhibits complement component C5a binding activity and complement component C5a receptor activity. Involved in several processes, including animal organ development; negative regulation of neuron apoptotic process; and response to lipopolysaccharide. Localizes to the cell surface and plasma membrane. Used to study adult respiratory distress syndrome; amyotrophic lateral sclerosis; neutropenia; obesity; and thrombosis. Biomarker of asthma and lung disease. Orthologous to human C5AR1 (complement C5a receptor 1) and OPRPN (opiorphin prepropeptide); PARTICIPATES IN coagulation cascade pathway; complement system pathway; Staphylococcus aureus infection pathway; INTERACTS WITH (RS)-amphetamine; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C5a anaphylatoxin chemotactic receptor; C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5aR; C5r1; complement C5a receptor; complement component 5, receptor 1; complement component 5a receptor 1
Orthologs:
Homo sapiens (human) : C5AR1 (complement C5a receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : C5ar1 (complement component 5a receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : C5ar1 (complement C5a receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : C5AR1 (complement C5a receptor 1)
Canis lupus familiaris (dog) : C5AR1 (complement C5a receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : C5ar1 (complement C5a receptor 1)
Sus scrofa (pig) : C5AR1 (complement C5a receptor 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0178,186,777 - 78,195,132 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0179,452,051 - 79,458,856 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera171,439,044 - 71,449,243 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on C5ar1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70553
Created: 2002-05-20
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.