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Gene: FGF2 (fibroblast growth factor 2) Homo sapiens
Symbol: FGF2
Name: fibroblast growth factor 2
Description: Exhibits nuclear receptor transcription coactivator activity and signaling receptor binding activity. Involved in several processes, including positive regulation of cell population proliferation; positive regulation of cellular metabolic process; and regulation of cell migration. Localizes to the extracellular space. Implicated in several diseases, including corneal neovascularization; diabetic neuropathy; gastric ulcer; impotence; and prostate adenocarcinoma. Biomarker of several diseases, including artery disease (multiple); breast cancer (multiple); carcinoma (multiple); eye disease (multiple); and female reproductive organ cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: basic fibroblast growth factor bFGF; BFGF; FGF-2; FGFB; fibroblast growth factor 2 (basic); HBGF-2; heparin-binding growth factor 2; prostatropin
Mus musculus (house mouse) : Fgf2 (fibroblast growth factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgf2 (fibroblast growth factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgf2 (fibroblast growth factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : FGF2 (fibroblast growth factor 2)
Canis lupus familiaris (dog) : FGF2 (fibroblast growth factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgf2 (fibroblast growth factor 2)
Sus scrofa (pig) : FGF2 (fibroblast growth factor 2)
Chlorocebus sabaeus (green monkey) : FGF2 (fibroblast growth factor 2)
Heterocephalus glaber (naked mole-rat) : Fgf2 (fibroblast growth factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl4122,826,708 - 122,898,236 (+)Ensembl
GRCh384122,826,708 - 122,898,236 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374123,747,568 - 123,819,390 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364123,967,313 - 124,038,840 (+)NCBINCBI36hg18NCBI36
Build 344124,105,467 - 124,176,995NCBI
Celera4121,130,707 - 121,202,234 (+)NCBI
Cytogenetic Map4q28.1NCBI
HuRef4119,474,437 - 119,545,817 (+)NCBIHuRef
CHM1_14123,724,372 - 123,795,895 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on FGF2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70822
Created: 2002-06-25
Species: Homo sapiens
Last Modified: 2020-01-14
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.