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Gene: MET (MET proto-oncogene, receptor tyrosine kinase) Homo sapiens
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Symbol: MET
Name: MET proto-oncogene, receptor tyrosine kinase
Description: Exhibits identical protein binding activity and protein phosphatase binding activity. Involved in several processes, including endothelial cell morphogenesis; negative regulation of signal transduction; and regulation of supramolecular fiber organization. Localizes to the basal plasma membrane. Implicated in autistic disorder; autosomal recessive nonsyndromic deafness 97; carcinoma (multiple); and multiple myeloma. Biomarker of arteriosclerosis; carcinoma (multiple); endocrine gland cancer (multiple); invasive ductal carcinoma; and sarcoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AUTS9; c-Met; cMet; DFNB97; hepatocyte growth factor receptor; HGF receptor; HGF/SF receptor; HGFR; mesenchymal-epithelial transition factor; met proto-oncogene tyrosine kinase; oncogene MET; OSFD; proto-oncogene c-Met; PTPRZ1/MET fusion; RCCP2; scatter factor receptor; SF receptor; soluble MET variant 12; tyrosine-protein kinase Met
Orthologs:
Mus musculus (house mouse) : Met (met proto-oncogene)  MGI  Alliance
Rattus norvegicus (Norway rat) : Met (MET proto-oncogene, receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Met (MET proto-oncogene, receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : MET (MET proto-oncogene, receptor tyrosine kinase)
Canis lupus familiaris (dog) : MET (MET proto-oncogene, receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Met (MET proto-oncogene, receptor tyrosine kinase)
Sus scrofa (pig) : MET (MET proto-oncogene, receptor tyrosine kinase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387116,672,196 - 116,798,386 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377116,312,406 - 116,438,440 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367116,099,695 - 116,225,676 (+)NCBINCBI36hg18NCBI36
Build 347115,906,409 - 116,032,390NCBI
Celera7111,119,882 - 111,245,969 (+)NCBI
Cytogenetic Map7q31.2NCBI
HuRef7110,678,023 - 110,804,134 (+)NCBIHuRef
CHM1_17116,246,017 - 116,372,044 (+)NCBICHM1_1
CRA_TCAGchr7v27115,707,906 - 115,833,890 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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