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Gene: CDK5 (cyclin dependent kinase 5) Homo sapiens
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Symbol: CDK5
Name: cyclin dependent kinase 5
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including negative regulation of nitrogen compound metabolic process; oligodendrocyte differentiation; and peptidyl-serine phosphorylation. Localizes to the nucleoplasm and plasma membrane. Predicted to colocalize with the microtubule. Implicated in Alzheimer's disease and lissencephaly.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cell division protein kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Orthologs:
Mus musculus (house mouse) : Cdk5 (cyclin-dependent kinase 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk5 (cyclin-dependent kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk5 (cyclin dependent kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK5 (cyclin dependent kinase 5)
Canis lupus familiaris (dog) : CDK5 (cyclin dependent kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk5 (cyclin dependent kinase 5)
Sus scrofa (pig) : CDK5 (cyclin dependent kinase 5)
more info ...
Related Pseudogenes: CDK5P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387151,053,815 - 151,057,897 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377150,750,899 - 150,755,052 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,381,832 - 150,385,929 (-)NCBINCBI36hg18NCBI36
Build 347150,188,546 - 150,192,644NCBI
Celera7145,308,208 - 145,312,361 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7144,563,235 - 144,567,388 (-)NCBIHuRef
CHM1_17150,759,247 - 150,763,400 (-)NCBICHM1_1
CRA_TCAGchr7v27150,080,438 - 150,084,591 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CDK5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70825
Created: 2002-06-25
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.