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Gene: CDK5 (cyclin dependent kinase 5) Homo sapiens
Symbol: CDK5
Name: cyclin dependent kinase 5
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including negative regulation of nitrogen compound metabolic process; oligodendrocyte differentiation; and peptidyl-serine phosphorylation. Localizes to the nucleoplasm and plasma membrane. Predicted to colocalize with the microtubule. Implicated in Alzheimer's disease and lissencephaly.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cell division protein kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Mus musculus (house mouse) : Cdk5 (cyclin-dependent kinase 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdk5 (cyclin-dependent kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk5 (cyclin dependent kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK5 (cyclin dependent kinase 5)
Canis lupus familiaris (dog) : CDK5 (cyclin dependent kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk5 (cyclin dependent kinase 5)
Sus scrofa (pig) : CDK5 (cyclin dependent kinase 5)
more info ...
Related Pseudogenes: CDK5P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh387151,053,815 - 151,057,897 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377150,750,899 - 150,755,052 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367150,381,832 - 150,385,929 (-)NCBINCBI36hg18NCBI36
Build 347150,188,546 - 150,192,644NCBI
Celera7145,308,208 - 145,312,361 (-)NCBI
Cytogenetic Map7q36.1NCBI
HuRef7144,563,235 - 144,567,388 (-)NCBIHuRef
CHM1_17150,759,247 - 150,763,400 (-)NCBICHM1_1
CRA_TCAGchr7v27150,080,438 - 150,084,591 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CDK5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70825
Created: 2002-06-25
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.