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Gene: Cdk5 (cyclin-dependent kinase 5) Mus musculus
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Symbol: Cdk5
Name: cyclin-dependent kinase 5
Description: Exhibits several functions, including Hsp90 protein binding activity; acetylcholine receptor activator activity; and signaling receptor binding activity. Involved in several processes, including chemical synaptic transmission; nervous system development; and regulation of cellular protein localization. Localizes to several cellular components, including axon; filopodium; and lamellipodium. Predicted to colocalize with microtubule. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly. Orthologous to human CDK5 (cyclin dependent kinase 5); PARTICIPATES IN dopamine signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; Reelin signaling pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 3,4-methylenedioxymethamphetamine; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW048668; cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin-dependent-like kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Orthologs:
Homo sapiens (human) : CDK5 (cyclin dependent kinase 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk5 (cyclin-dependent kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk5 (cyclin dependent kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK5 (cyclin dependent kinase 5)
Canis lupus familiaris (dog) : CDK5 (cyclin dependent kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk5 (cyclin dependent kinase 5)
Sus scrofa (pig) : CDK5 (cyclin dependent kinase 5)
Chlorocebus sabaeus (African green monkey) : CDK5 (cyclin dependent kinase 5)
Heterocephalus glaber (naked mole-rat) : Cdk5 (cyclin dependent kinase 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl524,418,241 - 24,423,530 (-)EnsemblGRCm38mm10GRCm38
GRCm38524,407,597 - 24,423,587 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37523,924,060 - 23,929,348 (-)NCBIGRCm37mm9NCBIm37
MGSCv36523,928,307 - 23,933,595 (-)NCBImm8
Celera521,368,049 - 21,373,342 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cdk5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70826
Created: 2002-06-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.