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Gene: Cdk5 (cyclin-dependent kinase 5) Mus musculus
Symbol: Cdk5
Name: cyclin-dependent kinase 5
Description: Exhibits several functions, including Hsp90 protein binding activity; acetylcholine receptor activator activity; and signaling receptor binding activity. Involved in several processes, including chemical synaptic transmission; nervous system development; and regulation of cellular protein localization. Localizes to several cellular components, including axon; filopodium; and lamellipodium. Predicted to colocalize with microtubule. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Alzheimer's disease and lissencephaly. Orthologous to human CDK5 (cyclin dependent kinase 5); PARTICIPATES IN dopamine signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; Reelin signaling pathway; INTERACTS WITH 2,3',4,4',5-Pentachlorobiphenyl; 3,4-methylenedioxymethamphetamine; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW048668; cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin-dependent-like kinase 5; serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit
Homo sapiens (human) : CDK5 (cyclin dependent kinase 5)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cdk5 (cyclin-dependent kinase 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdk5 (cyclin dependent kinase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : CDK5 (cyclin dependent kinase 5)
Canis lupus familiaris (dog) : CDK5 (cyclin dependent kinase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdk5 (cyclin dependent kinase 5)
Sus scrofa (pig) : CDK5 (cyclin dependent kinase 5)
Chlorocebus sabaeus (African green monkey) : CDK5 (cyclin dependent kinase 5)
Heterocephalus glaber (naked mole-rat) : Cdk5 (cyclin dependent kinase 5)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl524,418,241 - 24,423,530 (-)EnsemblGRCm38mm10GRCm38
GRCm38524,407,597 - 24,423,587 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37523,924,060 - 23,929,348 (-)NCBIGRCm37mm9NCBIm37
MGSCv36523,928,307 - 23,933,595 (-)NCBImm8
Celera521,368,049 - 21,373,342 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map511.73NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Cdk5
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70826
Created: 2002-06-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.