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Gene: PLD1 (phospholipase D1) Homo sapiens
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Symbol: PLD1
Name: phospholipase D1
Description: Predicted to have N-acylphosphatidylethanolamine-specific phospholipase D activity; phosphatidylinositol binding activity; and phospholipase D activity. Involved in regulation of microvillus assembly and regulation of synaptic vesicle cycle. Localizes to several cellular components, including the apical plasma membrane; cholinergic synapse; and cytoplasmic vesicle. Biomarker of pancreatic ductal adenocarcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: choline phosphatase 1; CVDD; hPLD1; phosphatidylcholine-hydrolyzing phospholipase D1; phospholipase D1, phosphatidylcholine-specific; PLD 1
Orthologs:
Mus musculus (house mouse) : Pld1 (phospholipase D1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pld1 (phospholipase D1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld1 (phospholipase D1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD1 (phospholipase D1)
Canis lupus familiaris (dog) : PLD1 (phospholipase D1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld1 (phospholipase D1)
Sus scrofa (pig) : PLD1 (phospholipase D1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383171,600,404 - 171,810,483 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373171,318,195 - 171,528,284 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363172,801,339 - 172,938,566 (-)NCBINCBI36hg18NCBI36
Build 343172,801,346 - 172,938,574NCBI
Celera3169,718,435 - 169,928,143 (-)NCBI
Cytogenetic Map3q26.31NCBI
HuRef3168,688,221 - 168,898,341 (-)NCBIHuRef
CHM1_13171,281,084 - 171,491,135 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLD1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70829
Created: 2002-06-25
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.