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Gene: Pld1 (phospholipase D1) Mus musculus
Symbol: Pld1
Name: phospholipase D1
Description: Predicted to have phospholipase D activity. Involved in defense response to Gram-positive bacterium. Predicted to localize to several cellular components, including Golgi cisterna; cholinergic synapse; and cytoplasmic vesicle. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in developmental cardiac valvular defect. Orthologous to human PLD1 (phospholipase D1); PARTICIPATES IN mTOR signaling pathway; ceramide signaling pathway; endocytosis pathway; INTERACTS WITH 1,1-dichloroethene; 1,2-dichloroethane; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA536939; C85393; choline phosphatase 1; mPLD1; phosphatidylcholine-hydrolyzing phospholipase D1; PLD 1; Pld1a; Pld1b
Homo sapiens (human) : PLD1 (phospholipase D1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pld1 (phospholipase D1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pld1 (phospholipase D1)
Pan paniscus (bonobo/pygmy chimpanzee) : PLD1 (phospholipase D1)
Canis lupus familiaris (dog) : PLD1 (phospholipase D1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pld1 (phospholipase D1)
Sus scrofa (pig) : PLD1 (phospholipase D1)
Chlorocebus sabaeus (African green monkey) : PLD1 (phospholipase D1)
Heterocephalus glaber (naked mole-rat) : Pld1 (phospholipase D1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl327,938,695 - 28,133,362 (+)EnsemblGRCm38mm10GRCm38
GRCm38327,938,459 - 28,133,362 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37327,837,602 - 28,032,284 (+)NCBIGRCm37mm9NCBIm37
MGSCv36328,215,231 - 28,324,307 (+)NCBImm8
Celera327,897,052 - 28,088,894 (+)NCBICelera
Cytogenetic Map3A3NCBI
cM Map311.15NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Pld1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70830
Created: 2002-06-25
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.