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Gene: Gnb3 (G protein subunit beta 3) Rattus norvegicus
Symbol: Gnb3
Name: G protein subunit beta 3
CRRD ID: 708344
Description: Exhibits spectrin binding activity. Predicted to be involved in several processes, including cell volume homeostasis; regulation of fat cell differentiation; and regulation of lipid metabolic process. Localizes to cell body and neuron projection. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; familial hyperlipidemia; mental depression; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3); PARTICIPATES IN visual phototransduction pathway; chemokine mediated signaling pathway; glutamate signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; clozapine.
Type: protein-coding
Also known as: G protein beta-subunit; G protein beta-subunit gene; guanine nucleotide binding protein (G protein), beta 3; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein, beta 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; guanine nucleotide-binding protein, beta-3 subunit; LOC60449; MGC105437; transducin beta chain 3
Homo sapiens (human) : GNB3 (G protein subunit beta 3)  HGNC  Alliance
Mus musculus (house mouse) : Gnb3 (guanine nucleotide binding protein (G protein), beta 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb3 (G protein subunit beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB3 (G protein subunit beta 3)
Canis lupus familiaris (dog) : GNB3 (G protein subunit beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb3 (G protein subunit beta 3)
Sus scrofa (pig) : GNB3 (G protein subunit beta 3)
Chlorocebus sabaeus (African green monkey) : GNB3 (G protein subunit beta 3)
Heterocephalus glaber (naked mole-rat) : Gnb3 (G protein subunit beta 3)
more info ...
Allele / Splice: Gnb3em1Mcwi  
Genetic Models: SS-Gnb3em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04157,352,558 - 157,359,237 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4157,352,372 - 157,358,262 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04224,370,234 - 224,376,918 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,957,524 - 160,963,226 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,202,460 - 161,208,162 (-)NCBI
Celera4146,377,383 - 146,383,085 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Gnb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708344
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.