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Gene: Gnb3 (G protein subunit beta 3) Rattus norvegicus
Symbol: Gnb3
Name: G protein subunit beta 3
Description: Exhibits spectrin binding activity. Predicted to be involved in several processes, including cell volume homeostasis; regulation of fat cell differentiation; and regulation of lipid metabolic process. Localizes to the cell body and neuron projection. Human ortholog(s) of this gene implicated in artery disease (multiple); congenital stationary night blindness 1H; familial hyperlipidemia; mental depression; and type 2 diabetes mellitus. Orthologous to human GNB3 (G protein subunit beta 3); PARTICIPATES IN visual phototransduction pathway; chemokine mediated signaling pathway; glutamate signaling pathway; INTERACTS WITH ammonium chloride; bisphenol A; clozapine.
Type: protein-coding
Also known as: G protein beta-subunit; G protein beta-subunit gene; guanine nucleotide binding protein (G protein), beta 3; guanine nucleotide binding protein (G protein), beta polypeptide 3; guanine nucleotide binding protein, beta 3; guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3; guanine nucleotide-binding protein, beta-3 subunit; LOC60449; MGC105437; transducin beta chain 3
Homo sapiens (human) : GNB3 (G protein subunit beta 3)  HGNC  Alliance
Mus musculus (house mouse) : Gnb3 (guanine nucleotide binding protein (G protein), beta 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnb3 (G protein subunit beta 3)
Pan paniscus (bonobo/pygmy chimpanzee) : GNB3 (G protein subunit beta 3)
Canis lupus familiaris (dog) : GNB3 (G protein subunit beta 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnb3 (G protein subunit beta 3)
Sus scrofa (pig) : GNB3 (G protein subunit beta 3)
more info ...
Allele / Splice: Gnb3em1Mcwi  
Genetic Models: SS-Gnb3em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.04157,352,558 - 157,359,237 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04224,370,234 - 224,376,918 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44160,957,524 - 160,963,226 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14161,202,460 - 161,208,162 (-)NCBI
Celera4146,377,383 - 146,383,085 (-)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Gnb3
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708344
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.