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Gene: HGF (hepatocyte growth factor) Homo sapiens
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Symbol: HGF
Name: hepatocyte growth factor
Description: Exhibits chemoattractant activity and identical protein binding activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; negative regulation of programmed cell death; and positive regulation of macromolecule metabolic process. Localizes to the membrane. Implicated in several diseases, including artery disease (multiple); autoimmune hypersensitivity disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); and neuropathy (multiple). Biomarker of several diseases, including artery disease (multiple); arthritis (multiple); biliary tract disease (multiple); myositis (multiple); and retinal disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deafness, autosomal recessive 39; DFNB39; F-TCF; fibroblast-derived tumor cytotoxic factor; hepatocyte growth factor (hepapoietin A, scatter factor); hepatopoeitin-A; hepatopoietin-A; HGFB; HPTA; lung fibroblast-derived mitogen; SF
Orthologs:
Mus musculus (house mouse) : Hgf (hepatocyte growth factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Hgf (hepatocyte growth factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hgf (hepatocyte growth factor)
Pan paniscus (bonobo/pygmy chimpanzee) : HGF (hepatocyte growth factor)
Canis lupus familiaris (dog) : HGF (hepatocyte growth factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hgf (hepatocyte growth factor)
Sus scrofa (pig) : HGF (hepatocyte growth factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38781,699,006 - 81,770,438 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37781,331,444 - 81,399,452 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,169,380 - 81,237,388 (-)NCBINCBI36hg18NCBI36
Build 34781,024,867 - 81,044,103NCBI
Celera776,032,788 - 76,100,524 (-)NCBI
Cytogenetic Map7q21.11NCBI
HuRef775,935,402 - 76,003,191 (-)NCBIHuRef
CHM1_1781,258,674 - 81,329,573 (-)NCBICHM1_1
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HGF
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70837
Created: 2002-06-25
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.