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Gene: Clcn4 (chloride voltage-gated channel 4) Rattus norvegicus
Symbol: Clcn4
Name: chloride voltage-gated channel 4
CRRD ID: 708381
Description: Predicted to have solute:proton antiporter activity and voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to localize to several cellular components, including Golgi apparatus; cytoplasmic vesicle; and lysosomal membrane. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability. Orthologous to human CLCN4 (chloride voltage-gated channel 4); INTERACTS WITH (+)-schisandrin B; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: chloride channel 4; chloride channel 4-2; chloride channel protein 4; chloride channel, voltage-sensitive 4; chloride transporter ClC-4; clC-4; Clcn4-2; h(+)/Cl(-) exchange transporter 4; MGC105433; putative chloride channel (similar to Mm Clcn4-2); putative chloride channel 4-2
Homo sapiens (human) : CLCN4 (chloride voltage-gated channel 4)  HGNC  Alliance
Mus musculus (house mouse) : Clcn4 (chloride channel, voltage-sensitive 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Clcn4 (chloride voltage-gated channel 4)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN4 (chloride voltage-gated channel 4)
Canis lupus familiaris (dog) : CLCN4 (chloride voltage-gated channel 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn4 (chloride voltage-gated channel 4)
Sus scrofa (pig) : CLCN4 (chloride voltage-gated channel 4)
Chlorocebus sabaeus (African green monkey) : CLCN4 (chloride voltage-gated channel 4)
Heterocephalus glaber (naked mole-rat) : Clcn4 (chloride voltage-gated channel 4)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X25,016,177 - 25,082,563 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX25,016,401 - 25,080,410 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X25,427,399 - 25,493,756 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X44,355,648 - 44,419,524 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X44,436,114 - 44,471,196 (+)NCBI
CeleraX24,157,917 - 24,221,792 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Clcn4
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708381
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.