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Gene: Cyp3a9 (cytochrome P450, family 3, subfamily a, polypeptide 9) Rattus norvegicus
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Symbol: Cyp3a9
Name: cytochrome P450, family 3, subfamily a, polypeptide 9
Description: Predicted to have estrogen 16-alpha-hydroxylase activity; oxidoreductase activity, acting on CH or CH2 groups; and testosterone 6-beta-hydroxylase activity. Involved in several processes, including response to dexamethasone; response to estradiol; and response to ethanol. Predicted to localize to the endoplasmic reticulum membrane and integral component of membrane. Human ortholog(s) of this gene implicated in chronic myeloid leukemia; essential hypertension; precursor B lymphoblastic lymphoma/leukemia; and precursor lymphoblastic lymphoma/leukemia. Orthologous to human CYP3A7-CYP3A51P (CYP3A7-CYP3A51P readthrough); CYP3A4 (cytochrome P450 family 3 subfamily A member 4); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5); PARTICIPATES IN artemether pharmacokinetics pathway; carbamazepine pharmacokinetics pathway; clopidogrel pharmacodynamics pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 3AH15; Cyp3a13; CYPIIIA9; cytochrome P450 3A9; cytochrome P450 olfactive 3; cytochrome P450, family 3, subfamily a, polypeptide 13; cytochrome P450-OLF3; MGC93139; olfactive; olfactory cytochrome P450olf3; P450-OLF3; P450olf3
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01219,074,288 - 19,114,491 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01221,132,926 - 21,173,248 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,164,384 - 17,204,589 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11217,153,354 - 17,193,208 (+)NCBI
Celera1218,744,706 - 18,784,438 (-)NCBICelera
Cytogenetic Map12q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cyp3a9
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708392
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.