Gene: Pias3 (protein inhibitor of activated STAT, 3) Rattus norvegicus
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Symbol: Pias3
Name: protein inhibitor of activated STAT, 3
Description: Exhibits potassium channel regulator activity, protein C-terminus binding activity, and protein N-terminus binding activity; involved in positive regulation of gene expression, positive regulation of membrane potential, and response to hormone; localizes to the dendrite, nucleus, and synapse; orthologous to human PIAS3 (protein inhibitor of activated STAT 3); PARTICIPATES IN sumoylation pathway; interleukin-6 signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: E3 SUMO-protein ligase PIAS3; E3 SUMO-protein transferase PIAS3; KChAP; LOC83614; potassium channel regulatory protein KChAP; potassium channel-associated protein; protein inhibitor of activated STAT 3; protein inhibitor of activated STAT protein 3
Orthologs:
Homo sapiens (human) : PIAS3 (protein inhibitor of activated STAT 3)  HGNC  Alliance
Mus musculus (house mouse) : Pias3 (protein inhibitor of activated STAT 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pias3 (protein inhibitor of activated STAT 3)
Pan paniscus (bonobo/pygmy chimpanzee) : PIAS3 (protein inhibitor of activated STAT 3)
Canis lupus familiaris (dog) : PIAS3 (protein inhibitor of activated STAT 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pias3 (protein inhibitor of activated STAT 3)
Sus scrofa (pig) : PIAS3 (protein inhibitor of activated STAT 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02198,821,377 - 198,831,533 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02218,309,595 - 218,318,467 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42191,499,057 - 191,507,221 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12191,461,810 - 191,469,975 (+)NCBI
Celera2176,757,800 - 176,765,964 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pias3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708413
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.