Gene: Cd40lg (CD40 ligand) Rattus norvegicus
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Symbol: Cd40lg
Name: CD40 ligand
Description: Exhibits CD40 receptor binding activity; involved in several processes, including cellular response to tumor necrosis factor, positive regulation of cytokine production, and positive regulation of macromolecule metabolic process; localizes to several cellular components, including the cell body, cell projection, and cell surface; used to study several diseases, including Ehrlich tumor carcinoma, anti-basement membrane glomerulonephritis, artery disease (multiple), thrombosis, and type 1 diabetes mellitus; biomarker of atherosclerosis, coronary artery disease, perinatal necrotizing enterocolitis, periodontal disease, and pulmonary hypertension; orthologous to human CD40LG (CD40 ligand); PARTICIPATES IN interleukin-4 signaling pathway; obesity pathway; allograft rejection pathway; INTERACTS WITH (RS)-amphetamine; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: CD40 ligand CD154; CD40-L; Cd40l; LOC84349; Tnfsf5; tumor necrosis factor (ligand) superfamily, member 5; tumor necrosis factor ligand superfamily member 5
Orthologs:
Homo sapiens (human) : CD40LG (CD40 ligand)  HGNC  Alliance
Mus musculus (house mouse) : Cd40lg (CD40 ligand)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cd40lg (CD40 ligand)
Pan paniscus (bonobo/pygmy chimpanzee) : CD40LG (CD40 ligand)
Canis lupus familiaris (dog) : CD40LG (CD40 ligand)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cd40lg (CD40 ligand)
Sus scrofa (pig) : CD40LG (CD40 ligand)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0X159,703,703 - 159,714,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0X154,330,893 - 154,341,954 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X141,925,019 - 141,937,183 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X141,998,451 - 142,010,616 (+)NCBI
CeleraX143,160,596 - 143,171,765 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Cd40lg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708418
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.