Gene: Sh3gl1 (SH3 domain containing GRB2 like 1, endophilin A2) Rattus norvegicus
Symbol: Sh3gl1
Name: SH3 domain containing GRB2 like 1, endophilin A2
Description: Exhibits several functions, including SH3 domain binding activity, beta-1 adrenergic receptor binding activity, and enzyme binding activity; involved in modulation of excitatory postsynaptic potential and positive regulation of synaptic vesicle endocytosis; localizes to several cellular components, including the Schaffer collateral - CA1 synapse, glutamatergic synapse, and hippocampal mossy fiber to CA3 synapse; used to study malignant glioma; orthologous to human SH3GL1 (SH3 domain containing GRB2 like 1, endophilin A2); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; INTERACTS WITH 2,4-dinitrotoluene; bisphenol A; cocaine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: endophilin-2; endophilin-A2; LOC81922; SH3 domain protein 2B; SH3 domain-containing GRB2-like 1; SH3 domain-containing GRB2-like protein 1; SH3-domain GRB2-like 1; SH3P8
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0911,031,847 - 11,055,285 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0910,018,274 - 10,040,574 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera97,637,327 - 7,660,492 (+)NCBICelera
Cytogenetic Map9q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
More on Sh3gl1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708456
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.