Ugt1a8 (UDP glucuronosyltransferase family 1 member A8) - Chinchilla Research Resource Database

Gene: Ugt1a8 (UDP glucuronosyltransferase family 1 member A8) Rattus norvegicus

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Symbol:

Ugt1a8

Name:

UDP glucuronosyltransferase family 1 member A8

Description:

Exhibits glucuronosyltransferase activity. Involved in cellular response to organic cyclic compound and coumarin catabolic process. Localizes to the membrane. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic cancer. Orthologous to several human genes including UGT1A8 (UDP glucuronosyltransferase family 1 member A8); PARTICIPATES IN codeine and morphine pharmacodynamics pathway; codeine and morphine pharmacokinetics pathway; mycophenolic acid pharmacokinetics pathway; INTERACTS WITH 1-naphthol; 17alpha-ethynylestradiol; 4-methylumbelliferone.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

A3; UDP glycosyltransferase 1 family, polypeptide A8; UDP-glucuronosyltransferase 1-8; UDP-glucuronosyltransferase 1A8; UDPGT; UDPGT 1-8; Ugt1; UGT1*8; UGT1-08; UGT1.8; Ugt1a9

Orthologs:

Homo sapiens (human) : UGT1A8 (UDP glucuronosyltransferase family 1 member A8) HGNC Alliance

more info ...

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	UGT1A8 (UDP glucuronosyltransferase family 1 member A8)	HGNC	HomoloGene, Panther
Other homologs ²
Homo sapiens (human):	UGT1A10 (UDP glucuronosyltransferase family 1 member A10)	HGNC	HomoloGene, Panther
Homo sapiens (human):	UGT1A9 (UDP glucuronosyltransferase family 1 member A9)	HGNC	HomoloGene, Panther
Homo sapiens (human):	UGT1A7 (UDP glucuronosyltransferase family 1 member A7)	HGNC	HomoloGene, Panther
Homo sapiens (human):	UGT2A1 (UDP glucuronosyltransferase family 2 member A1 complex locus)	HGNC	Panther
Homo sapiens (human):	UGT2B10 (UDP glucuronosyltransferase family 2 member B10)	HGNC	Panther
Homo sapiens (human):	UGT8 (UDP glycosyltransferase 8)	HGNC	Panther
Homo sapiens (human):	UGT2B15 (UDP glucuronosyltransferase family 2 member B15)	HGNC	Panther
Homo sapiens (human):	UGT2B4 (UDP glucuronosyltransferase family 2 member B4)	HGNC	Panther
Homo sapiens (human):	UGT2B11 (UDP glucuronosyltransferase family 2 member B11)	HGNC	Panther
Homo sapiens (human):	UGT2B28 (UDP glucuronosyltransferase family 2 member B28)	HGNC	Panther
Homo sapiens (human):	UGT2B17 (UDP glucuronosyltransferase family 2 member B17)	HGNC	Panther
Homo sapiens (human):	UGT2B7 (UDP glucuronosyltransferase family 2 member B7)	HGNC	Panther
Homo sapiens (human):	UGT3A1 (UDP glycosyltransferase family 3 member A1)	HGNC	Panther
Homo sapiens (human):	UGT3A2 (UDP glycosyltransferase family 3 member A2)	HGNC	Panther
Homo sapiens (human):	UGT2A3 (UDP glucuronosyltransferase family 2 member A3)	HGNC	Panther
Alliance orthologs ³
Homo sapiens (human):	UGT1A8 (UDP glucuronosyltransferase family 1 member A8)	Alliance	DIOPT (HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Homo sapiens (human):	UGT1A10 (UDP glucuronosyltransferase family 1 member A10)	Alliance	DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Homo sapiens (human):	UGT1A9 (UDP glucuronosyltransferase family 1 member A9)	Alliance	DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Homo sapiens (human):	UGT1A7 (UDP glucuronosyltransferase family 1 member A7)	Alliance	DIOPT (Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Mus musculus (house mouse):	Ugt1a9 (UDP glucuronosyltransferase 1 family, polypeptide A9)	Alliance	DIOPT (Hieranoid, OrthoFinder)
Danio rerio (zebrafish):	ugt1ab (UDP glucuronosyltransferase 1 family a, b)	Alliance	DIOPT (InParanoid, OrthoFinder, OrthoInspector, PhylomeDB)
Danio rerio (zebrafish):	ugt1b7 (UDP glucuronosyltransferase 1 family, polypeptide B7)	Alliance	DIOPT (InParanoid, OrthoFinder, OrthoInspector, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG10168	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	F10D2.8	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-3	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-37	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-7	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG10170	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	K04A8.10	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-43	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-44	Alliance	DIOPT (Hieranoid, OrthoFinder, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG10178	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-10	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-11	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-12	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-13	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-14	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-15	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-16	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-17	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-18	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-20	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-22	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-23	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-24	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-26	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-27	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-28	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-29	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-30	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-32	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-66	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-8	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-9	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-46	Alliance	DIOPT (OrthoFinder, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-47	Alliance	DIOPT (OrthoFinder, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-48	Alliance	DIOPT (OrthoFinder, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG15661	Alliance	DIOPT (Hieranoid, InParanoid, OMA, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG16732	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-19	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-21	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-35	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-4	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-41	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-42	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-6	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG17322	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG17323	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG17324	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-59	Alliance	DIOPT (OrthoFinder, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG31002	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt37c1	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Dc	Alliance	DIOPT (Hieranoid, InParanoid, OMA, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86De	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Dj	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG4302	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Dot	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Dh	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Di	Alliance	DIOPT (Hieranoid, InParanoid, OMA, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	H23N18.4	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG5724	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG5999	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt37a1	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt37b1	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt36Bb	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	CG3797	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-1	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-2	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-25	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt36Ba	Alliance	DIOPT (Hieranoid, OMA, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt36Bc	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-33	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Da	Alliance	DIOPT (Hieranoid, InParanoid, OMA, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-34	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-36	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-38	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-39	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-40	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-5	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)
Drosophila melanogaster (fruit fly):	Ugt86Dd	Alliance	DIOPT (Hieranoid, InParanoid, PANTHER, PhylomeDB)
Caenorhabditis elegans (roundworm):	ugt-31	Alliance	DIOPT (Hieranoid, PANTHER, PhylomeDB)

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	9	95,221,474 - 95,302,822 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	9	95,161,157 - 95,302,822 (+)	Ensembl
Rnor_5.0	9	94,910,377 - 94,990,037 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	9	87,017,029 - 87,098,362 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	9	87,202,433 - 87,284,226 (+)	NCBI
Celera	9	86,288,443 - 86,369,556 (+)	NCBI		Celera
Cytogenetic Map	9	q35	NCBI

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Model

Annotation (Toggle Annotation Detail/Summary View)

Disease Annotations

Gene-Chemical Interaction Annotations

Gene Ontology Annotations

Molecular Pathway Annotations

References - curated

References - uncurated

Genomics

Comparative Map Data

Position Markers

QTLs in Region (Rnor_6.0)

miRNA Target Status

Expression

Sequence

Nucleotide Sequences

Protein Sequences

Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Damaging Variants

Additional Information

External Database Links

Nomenclature History

More on Ugt1a8
	Alliance Gene
	NCBI Gene
	Ensembl Gene
	JBrowse: rn5 rn6
	NCBI Genome Data Viewer

CRRD Object Information
CRRD ID:	708474
Created:	2003-09-23
Species:	Rattus norvegicus
Last Modified:	2019-11-27
Status:	ACTIVE

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
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MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Annotations - ClinVar

Imported Annotations - SMPDB

Imported Annotations - KEGG (archival)