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Gene: Mark2 (microtubule affinity regulating kinase 2) Rattus norvegicus
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Symbol: Mark2
Name: microtubule affinity regulating kinase 2
Description: Exhibits kinase activity; protein N-terminus binding activity; and tau protein binding activity. Involved in several processes, including cellular protein modification process; establishment or maintenance of cell polarity regulating cell shape; and generation of neurons. Localizes to the membrane. Orthologous to human MARK2 (microtubule affinity regulating kinase 2); PARTICIPATES IN Notch signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ELKL motif kinase 1; EMK-1; EMK1; LOC60328; MAP/microtubule affinity-regulating kinase 2; serine/threonine kinase; serine/threonine-protein kinase MARK2
Orthologs:
Homo sapiens (human) : MARK2 (microtubule affinity regulating kinase 2)  HGNC  Alliance
Mus musculus (house mouse) : Mark2 (MAP/microtubule affinity regulating kinase 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mark2 (microtubule affinity regulating kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MARK2 (microtubule affinity regulating kinase 2)
Canis lupus familiaris (dog) : MARK2 (microtubule affinity regulating kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mark2 (microtubule affinity regulating kinase 2)
Sus scrofa (pig) : MARK2 (microtubule affinity regulating kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01222,525,547 - 222,590,727 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01229,514,726 - 229,578,616 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,958,902 - 210,022,099 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11210,117,331 - 210,180,529 (-)NCBI
Celera1201,995,334 - 202,058,517 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
 
More on Mark2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708483
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.