Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Aacs (acetoacetyl-CoA synthetase) Rattus norvegicus
Analyze
Symbol: Aacs
Name: acetoacetyl-CoA synthetase
Description: Exhibits acetoacetate-CoA ligase activity and butyrate-CoA ligase activity. Involved in several processes, including cellular response to glucose stimulus; cellular response to lipid; and positive regulation of insulin secretion. Localizes to the cytosol. Biomarker of obesity. Orthologous to human AACS (acetoacetyl-CoA synthetase); PARTICIPATES IN ketone bodies metabolic pathway; butanoate metabolic pathway; INTERACTS WITH (S)-nicotine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AcAc-CoA ligase; acetoacetate-CoA ligase; acetoacetyl-CoA ligase; LOC65984
Orthologs:
Homo sapiens (human) : AACS (acetoacetyl-CoA synthetase)  HGNC  Alliance
Mus musculus (house mouse) : Aacs (acetoacetyl-CoA synthetase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Aacs (acetoacetyl-CoA synthetase)
Pan paniscus (bonobo/pygmy chimpanzee) : AACS (acetoacetyl-CoA synthetase)
Canis lupus familiaris (dog) : AACS (acetoacetyl-CoA synthetase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Aacs (acetoacetyl-CoA synthetase)
Sus scrofa (pig) : AACS (acetoacetyl-CoA synthetase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01236,512,393 - 36,555,694 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01238,381,585 - 38,425,026 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41232,206,863 - 32,250,583 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11232,070,250 - 32,113,971 (-)NCBI
Celera1232,807,686 - 32,851,029 (-)NCBICelera
Cytogenetic Map12q14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Aacs
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708522
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.