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Gene: Dclre1c (DNA cross-link repair 1C) Rattus norvegicus
Symbol: Dclre1c
Name: DNA cross-link repair 1C
Description: Predicted to have 5'-3' exodeoxyribonuclease activity; damaged DNA binding activity; and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in B cell differentiation; DNA metabolic process; and response to ionizing radiation. Predicted to localize to Golgi apparatus; nonhomologous end joining complex; and nuclear lumen. Human ortholog(s) of this gene implicated in Omenn syndrome; common variable immunodeficiency; severe combined immunodeficiency; and severe combined immunodeficiency with sensitivity to ionizing radiation. Orthologous to human DCLRE1C (DNA cross-link repair 1C); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; primary immunodeficiency pathway; INTERACTS WITH 2,4-dinitrotoluene; acrylamide; ammonium chloride.
Type: protein-coding
Also known as: DNA cross-link repair 1C protein; DNA cross-link repair 1C, PSO2 homolog; DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae); protein artemis; SNM1-like; Snm1l
Homo sapiens (human) : DCLRE1C (DNA cross-link repair 1C)  HGNC  Alliance
Mus musculus (house mouse) : Dclre1c (DNA cross-link repair 1C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dclre1c (DNA cross-link repair 1C)
Pan paniscus (bonobo/pygmy chimpanzee) : DCLRE1C (DNA cross-link repair 1C)
Canis lupus familiaris (dog) : DCLRE1C (DNA cross-link repair 1C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dclre1c (DNA cross-link repair 1C)
Sus scrofa (pig) : DCLRE1C (DNA cross-link repair 1C)
Chlorocebus sabaeus (African green monkey) : DCLRE1C (DNA cross-link repair 1C)
Heterocephalus glaber (naked mole-rat) : Dclre1c (DNA cross-link repair 1C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01778,782,512 - 78,812,140 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1778,783,437 - 78,812,111 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01780,427,567 - 80,455,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,896,581 - 85,928,644 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11785,907,414 - 85,939,509 (-)NCBI
Celera1774,162,589 - 74,190,482 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Dclre1c
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708574
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.