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Gene: Dclre1c (DNA cross-link repair 1C) Rattus norvegicus
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Symbol: Dclre1c
Name: DNA cross-link repair 1C
Description: Predicted to have 5'-3' exodeoxyribonuclease activity; damaged DNA binding activity; and single-stranded DNA endodeoxyribonuclease activity. Predicted to be involved in B cell differentiation; DNA metabolic process; and response to ionizing radiation. Predicted to localize to the Golgi apparatus; nonhomologous end joining complex; and nucleus. Human ortholog(s) of this gene implicated in Omenn syndrome; common variable immunodeficiency; severe combined immunodeficiency; and severe combined immunodeficiency with sensitivity to ionizing radiation. Orthologous to human DCLRE1C (DNA cross-link repair 1C); PARTICIPATES IN non-homologous end joining pathway of double-strand break repair; primary immunodeficiency pathway; INTERACTS WITH 2,4-dinitrotoluene; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA cross-link repair 1C protein; DNA cross-link repair 1C, PSO2 homolog; DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae); protein artemis; SNM1-like; Snm1l
Orthologs:
Homo sapiens (human) : DCLRE1C (DNA cross-link repair 1C)  HGNC  Alliance
Mus musculus (house mouse) : Dclre1c (DNA cross-link repair 1C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dclre1c (DNA cross-link repair 1C)
Pan paniscus (bonobo/pygmy chimpanzee) : DCLRE1C (DNA cross-link repair 1C)
Canis lupus familiaris (dog) : DCLRE1C (DNA cross-link repair 1C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dclre1c (DNA cross-link repair 1C)
Sus scrofa (pig) : DCLRE1C (DNA cross-link repair 1C)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01778,782,512 - 78,812,140 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01780,427,567 - 80,455,846 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41785,896,581 - 85,928,644 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11785,907,414 - 85,939,509 (-)NCBI
Celera1774,162,589 - 74,190,482 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Dclre1c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 708574
Created: 2003-09-23
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.