Gene: Dbn1 (drebrin 1) Rattus norvegicus
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Symbol: Dbn1
Name: drebrin 1
Description: Exhibits actin filament binding activity and profilin binding activity; involved in several processes, including modulation of chemical synaptic transmission, nervous system development, and regulation of organelle organization; localizes to several cellular components, including the cell-cell junction, excitatory synapse, and neuron projection; colocalizes with the actin filament; biomarker of Parkinson's disease, cognitive disorder, sciatic neuropathy, temporal lobe epilepsy, and transient cerebral ischemia; orthologous to human DBN1 (drebrin 1); INTERACTS WITH (RS)-amphetamine; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: developmentally-regulated brain protein; drebrin; drebrin E
Orthologs:
Homo sapiens (human) : DBN1 (drebrin 1)  HGNC  Alliance
Mus musculus (house mouse) : Dbn1 (drebrin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dbn1 (drebrin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DBN1 (drebrin 1)
Canis lupus familiaris (dog) : DBN1 (drebrin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dbn1 (drebrin 1)
Sus scrofa (pig) : DBN1 (drebrin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0179,679,511 - 9,693,878 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01711,788,527 - 11,802,863 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41715,194,687 - 15,208,660 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11715,194,686 - 15,208,660 (+)NCBI
Celera179,229,222 - 9,243,194 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Dbn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70885
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-05-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.