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Gene: Gk (glycerol kinase) Rattus norvegicus
Symbol: Gk
Name: glycerol kinase
CRRD ID: 70893
Description: Exhibits histone binding activity. Involved in response to cold; response to drug; and response to ethanol. Localizes to mitochondrion and nucleus. Used to study familial hypercholesterolemia. Human ortholog(s) of this gene implicated in glycerol kinase deficiency. Orthologous to human GK (glycerol kinase); PARTICIPATES IN D-glycericacidemia pathway; familial lipoprotein lipase deficiency pathway; glycerol kinase deficiency pathway; INTERACTS WITH (R)-noradrenaline; 1-naphthyl isothiocyanate; 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ASTP; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; ATP:glycerol 3-phosphotransferase; glycerokinase; Gyk
Homo sapiens (human) : GK (glycerol kinase)  HGNC  Alliance
Mus musculus (house mouse) : Gk (glycerol kinase)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gk (glycerol kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : GK (glycerol kinase)
Canis lupus familiaris (dog) : GK (glycerol kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gk (glycerol kinase)
Sus scrofa (pig) : GK (glycerol kinase)
Chlorocebus sabaeus (African green monkey) : GK (glycerol kinase)
Heterocephalus glaber (naked mole-rat) : Gk (glycerol kinase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X54,227,291 - 54,303,897 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX54,227,397 - 54,303,864 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X54,426,876 - 54,503,386 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X72,416,872 - 72,493,296 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X72,491,081 - 72,566,588 (-)NCBI
CeleraX50,789,241 - 50,865,448 (-)NCBICelera
Cytogenetic MapXq21NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gk
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70893
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.