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Gene: Ddx39b (DExD-box helicase 39B) Rattus norvegicus
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Symbol: Ddx39b
Name: DExD-box helicase 39B
Description: Predicted to have several functions, including ATP-dependent protein binding activity; ATPase activity; and RNA binding activity. Involved in several processes, including positive regulation of cell growth involved in cardiac muscle cell development; positive regulation of macromolecule biosynthetic process; and positive regulation of vascular smooth muscle cell proliferation. Localizes to the nuclear matrix and protein-containing complex. Predicted to colocalize with the U4 snRNP; U6 snRNP; and cytoplasm. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus. Orthologous to human DDX39B (DExD-box helicase 39B); PARTICIPATES IN NXF1-NXT1 export pathway; spliceosome pathway; INTERACTS WITH 2,4-dinitrotoluene; 3-chloropropane-1,2-diol; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 56 kDa U2AF65-associated protein; ATP-dependent RNA helicase p47; Bat1; Bat1a; D17H6S81E-1; D20H6S81e; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B; DEAD box protein UAP56; DEAD-box helicase 39B; DNA segment Chr 17 human D6S81E 1; HLA-B associated transcript 1; HLA-B associated transcript 1A; HLA-B-associated transcript 1A; Nuclear RNA helicase; p47; spliceosome RNA helicase Bat1; spliceosome RNA helicase Ddx39b
Orthologs:
Homo sapiens (human) : DDX39B (DExD-box helicase 39B)  HGNC  Alliance
Mus musculus (house mouse) : Ddx39b (DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ddx39b (DExD-box helicase 39B)
Pan paniscus (bonobo/pygmy chimpanzee) : DDX39B (DExD-box helicase 39B)
Canis lupus familiaris (dog) : DDX39B (DExD-box helicase 39B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ddx39b (DExD-box helicase 39B)
Sus scrofa (pig) : DDX39B (DExD-box helicase 39B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0204,806,103 - 4,818,600 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0206,886,503 - 6,898,979 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,611,128 - 3,623,578 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,611,355 - 3,623,754 (-)NCBI
Celera204,440,470 - 4,452,912 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ddx39b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70923
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.