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Gene: Mgst1 (microsomal glutathione S-transferase 1) Rattus norvegicus
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Symbol: Mgst1
Name: microsomal glutathione S-transferase 1
Description: Exhibits glutathione binding activity; glutathione transferase activity; and protein homodimerization activity. Involved in several processes, including Leydig cell differentiation; protein homotrimerization; and response to lipopolysaccharide. Localizes to several cellular components, including the apical part of cell; endoplasmic reticulum; and peroxisomal membrane. Orthologous to human MGST1 (microsomal glutathione S-transferase 1); PARTICIPATES IN glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH (+)-schisandrin B; (-)-epigallocatechin 3-gallate; (S)-amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MGC72699; microsomal GST-1; microsomal GST-I
Orthologs:
Homo sapiens (human) : MGST1 (microsomal glutathione S-transferase 1)  HGNC  Alliance
Mus musculus (house mouse) : Mgst1 (microsomal glutathione S-transferase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mgst1 (microsomal glutathione S-transferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MGST1 (microsomal glutathione S-transferase 1)
Canis lupus familiaris (dog) : MGST1 (microsomal glutathione S-transferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mgst1 (microsomal glutathione S-transferase 1)
Sus scrofa (pig) : MGST1 (microsomal glutathione S-transferase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04172,119,382 - 172,134,609 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04236,372,225 - 236,387,452 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44175,248,654 - 175,263,881 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14175,493,783 - 175,509,005 (+)NCBI
Celera4159,602,240 - 159,617,460 (+)NCBICelera
Cytogenetic Map4q44NCBI
RH 3.4 Map41032.9RGD
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mgst1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70927
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.