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Gene: Cpn1 (carboxypeptidase N subunit 1) Rattus norvegicus
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Symbol: Cpn1
Name: carboxypeptidase N subunit 1
Description: Exhibits carboxypeptidase activity. Involved in bradykinin catabolic process; proteolysis; and response to glucocorticoid. Localizes to the extracellular space. Orthologous to human CPN1 (carboxypeptidase N subunit 1); PARTICIPATES IN kallikrein-kinin cascade pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: carboxypeptidase N; carboxypeptidase N catalytic chain; carboxypeptidase N catalytic chain-like; carboxypeptidase N small subunit; carboxypeptidase N, polypeptide 1; carboxypeptidase N, polypeptide 1, 50kD; Cpn; LOC100361985; MGC108636
Orthologs:
Homo sapiens (human) : CPN1 (carboxypeptidase N subunit 1)  HGNC  Alliance
Mus musculus (house mouse) : Cpn1 (carboxypeptidase N, polypeptide 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cpn1 (carboxypeptidase N subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CPN1 (carboxypeptidase N subunit 1)
Canis lupus familiaris (dog) : CPN1 (carboxypeptidase N subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cpn1 (carboxypeptidase N subunit 1)
Sus scrofa (pig) : CPN1 (carboxypeptidase N subunit 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: spans an assembly gap
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01263,733,887 - 263,762,758 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01271,179,096 - 271,207,752 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.11249,503,283 - 249,516,546NCBI
Celera1238,661,460 - 238,690,684 (-)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cpn1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70931
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.