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Gene: Mapk8ip1 (mitogen-activated protein kinase 8 interacting protein 1) Rattus norvegicus
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Symbol: Mapk8ip1
Name: mitogen-activated protein kinase 8 interacting protein 1
Description: Exhibits identical protein binding activity and kinase binding activity. Involved in negative regulation of JUN kinase activity; negative regulation of apoptotic process; and signal transduction. Localizes to cytosol; growth cone; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MAPK8IP1 (mitogen-activated protein kinase 8 interacting protein 1); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: C-jun-amino-terminal kinase-interacting protein 1; IB-1; islet-brain-1; Jip-1; JIP-1-related protein; JIP1; JNK MAP kinase scaffold protein 1; JNK-interacting protein 1; JRP; Mapk8ip; mitogen activated protein kinase 8 interacting protein; mitogen-activated protein kinase 8-interacting protein 1
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0381,295,023 - 81,304,181 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl381,295,024 - 81,304,181 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0387,998,491 - 88,016,191 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4376,781,504 - 76,790,661 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1376,677,932 - 76,687,089 (-)NCBI
Celera377,557,046 - 77,566,196 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mapk8ip1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70937
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.