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Gene: Glrx (glutaredoxin) Rattus norvegicus
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Symbol: Glrx
Name: glutaredoxin
Description: Exhibits glutathione disulfide oxidoreductase activity. Involved in several processes, including cellular response to estradiol stimulus; positive regulation of secretion by cell; and regulation of signal transduction. Localizes to several cellular components, including the dendrite; mitochondrial intermembrane space; and neuronal cell body. Biomarker of obesity and transient cerebral ischemia. Orthologous to human GLRX (glutaredoxin); INTERACTS WITH (RS)-amphetamine; 17alpha-ethynylestradiol; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Glrx1; glutaredoxin (thioltransferase); glutaredoxin 1; glutaredoxin 1 (thioltransferase); glutaredoxin-1; Grx; thioltransferase-1; TTase-1
Orthologs:
Homo sapiens (human) : GLRX (glutaredoxin)  HGNC  Alliance
Mus musculus (house mouse) : Glrx (glutaredoxin)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Glrx (glutaredoxin)
Pan paniscus (bonobo/pygmy chimpanzee) : GLRX (glutaredoxin)
Canis lupus familiaris (dog) : GLRX (glutaredoxin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Glrx (glutaredoxin)
Sus scrofa (pig) : GLRX (glutaredoxin)
more info ...
Related Pseudogenes: LOC100362708   LOC100362736   LOC290508   LOC305806  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.022,606,032 - 2,615,944 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.022,604,479 - 2,614,391 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.422,888,605 - 2,899,216 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.122,908,046 - 2,918,657 (+)NCBI
Celera21,812,028 - 1,821,780 (+)NCBICelera
Cytogenetic Map2q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Glrx
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70951
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.