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Gene: Gsto1 (glutathione S-transferase omega 1) Rattus norvegicus
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Symbol: Gsto1
Name: glutathione S-transferase omega 1
Description: Exhibits glutathione dehydrogenase (ascorbate) activity. Involved in L-ascorbic acid biosynthetic process. Localizes to several cellular components, including cell body; myelin sheath; and nuclear membrane. Human ortholog(s) of this gene implicated in Alzheimer's disease and Parkinson's disease. Orthologous to human GSTO1 (glutathione S-transferase omega 1); PARTICIPATES IN glutathione conjugation pathway; glutathione metabolic pathway; phase I biotransformation pathway via cytochrome P450; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glutathione S-transferase omega 1-1; glutathione S-transferase omega-1; glutathione-dependent dehydroascorbate reductase; GSTO 1-1; GSTO-1; MGC94845; MMA(V) reductase; monomethylarsonic acid reductase; S-(Phenacyl)glutathione reductase; SPG-R
Orthologs:
Homo sapiens (human) : GSTO1 (glutathione S-transferase omega 1)  HGNC  Alliance
Mus musculus (house mouse) : Gsto1 (glutathione S-transferase omega 1)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GSTO1 (glutathione S-transferase omega 1)
Canis lupus familiaris (dog) : GSTO1 (glutathione S-transferase omega 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gsto1 (glutathione S-transferase omega 1)
Sus scrofa (pig) : GSTO1 (glutathione S-transferase omega 1)
Chlorocebus sabaeus (African green monkey) : GSTO1 (glutathione S-transferase omega 1)
Heterocephalus glaber (naked mole-rat) : Gsto1 (glutathione S-transferase omega 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01267,607,437 - 267,617,387 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1267,607,418 - 267,617,387 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01275,040,049 - 275,050,033 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41253,228,547 - 253,238,531 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11253,493,307 - 253,503,274 (+)NCBI
Celera1242,486,178 - 242,496,113 (+)NCBICelera
Cytogenetic Map1q54NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gsto1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70952
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.