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Gene: Mapk12 (mitogen-activated protein kinase 12) Rattus norvegicus
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Symbol: Mapk12
Name: mitogen-activated protein kinase 12
Description: Exhibits ATP binding activity and MAP kinase activity. Involved in negative regulation of cell cycle and protein phosphorylation. Localizes to the cytoplasm. Orthologous to human MAPK12 (mitogen-activated protein kinase 12); PARTICIPATES IN p38 MAPK signaling pathway; amyotrophic lateral sclerosis pathway; Chagas disease pathway; INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: ERK-6; extracellular signal-regulated kinase 6; MAP kinase 12; MAP kinase p38 gamma; MAPK 12; MGC156834; mitogen-activated protein kinase p38 gamma; SAP kinase-3; Sapk3; stress-activated protein kinase 3
Orthologs:
Homo sapiens (human) : MAPK12 (mitogen-activated protein kinase 12)  HGNC  Alliance
Mus musculus (house mouse) : Mapk12 (mitogen-activated protein kinase 12)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk12 (mitogen-activated protein kinase 12)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK12 (mitogen-activated protein kinase 12)
Canis lupus familiaris (dog) : MAPK12 (mitogen-activated protein kinase 12)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk12 (mitogen-activated protein kinase 12)
Sus scrofa (pig) : MAPK12 (mitogen-activated protein kinase 12)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.07130,109,214 - 130,120,918 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.07129,795,269 - 129,805,662 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47127,430,881 - 127,441,274 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.17127,465,110 - 127,475,504 (-)NCBI
Celera7116,680,166 - 116,690,559 (-)NCBICelera
Cytogenetic Map7q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Mapk12
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70975
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.