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Gene: Flot1 (flotillin 1) Rattus norvegicus
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Symbol: Flot1
Name: flotillin 1
Description: Exhibits ionotropic glutamate receptor binding activity and protease binding activity. Predicted to be involved in several processes, including positive regulation of cell-cell adhesion; positive regulation of cellular component organization; and protein localization to membrane. Localizes to several cellular components, including the GABA-ergic synapse; flotillin complex; and glutamatergic synapse. Predicted to colocalize with the COP9 signalosome and cortical actin cytoskeleton. Orthologous to human FLOT1 (flotillin 1); PARTICIPATES IN insulin signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: flotillin-1; Rareg; REG-2; reggie-2
Orthologs:
Homo sapiens (human) : FLOT1 (flotillin 1)  HGNC  Alliance
Mus musculus (house mouse) : Flot1 (flotillin 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flot1 (flotillin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FLOT1 (flotillin 1)
Canis lupus familiaris (dog) : FLOT1 (flotillin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flot1 (flotillin 1)
Sus scrofa (pig) : FLOT1 (flotillin 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0203,427,890 - 3,438,418 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0205,524,708 - 5,535,232 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,065,792 - 3,076,166 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1203,066,008 - 3,169,167 (-)NCBI
Celera20343,778 - 353,887 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Flot1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 70991
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.