Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hspb8 (heat shock protein family B (small) member 8) Rattus norvegicus
Symbol: Hspb8
Name: heat shock protein family B (small) member 8
Description: Predicted to have protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to localize to chaperone complex; cytosol; and nuclear body. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L and distal hereditary motor neuronopathy type 2A. Orthologous to human HSPB8 (heat shock protein family B (small) member 8); INTERACTS WITH 1,3-dinitrobenzene; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: alpha-crystallin C chain; Cryac; crystallin, alpha C; heat shock 22kDa protein 8; heat shock protein 8; heat shock protein B8; heat shock protein beta-8; Hsp22; MGC72354; small stress protein-like protein HSP22
Homo sapiens (human) : HSPB8 (heat shock protein family B (small) member 8)  HGNC  Alliance
Mus musculus (house mouse) : Hspb8 (heat shock protein 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspb8 (heat shock protein family B (small) member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPB8 (heat shock protein family B (small) member 8)
Canis lupus familiaris (dog) : HSPB8 (heat shock protein family B (small) member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965479 (uncharacterized LOC101965479)
Sus scrofa (pig) : HSPB8 (heat shock protein family B (small) member 8)
Chlorocebus sabaeus (African green monkey) : HSPB8 (heat shock protein family B (small) member 8)
Heterocephalus glaber (naked mole-rat) : Hspb8 (heat shock protein family B (small) member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01245,905,371 - 45,920,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1245,905,371 - 45,920,013 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01247,717,762 - 47,731,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41241,407,166 - 41,421,565 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11241,270,553 - 41,284,952 (+)NCBI
Celera1241,813,553 - 41,828,157 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Hspb8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71003
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.