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Gene: Hspb8 (heat shock protein family B (small) member 8) Rattus norvegicus
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Symbol: Hspb8
Name: heat shock protein family B (small) member 8
Description: Predicted to have protein homodimerization activity. Predicted to be involved in cellular response to unfolded protein and positive regulation of aggrephagy. Predicted to localize to the chaperone complex; cytosol; and nucleus. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2L. Orthologous to human HSPB8 (heat shock protein family B (small) member 8); INTERACTS WITH (RS)-amphetamine; 1,3-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha-crystallin C chain; Cryac; crystallin, alpha C; heat shock 22kDa protein 8; heat shock protein 8; heat shock protein B8; heat shock protein beta-8; Hsp22; MGC72354; small stress protein-like protein HSP22
Orthologs:
Homo sapiens (human) : HSPB8 (heat shock protein family B (small) member 8)  HGNC  Alliance
Mus musculus (house mouse) : Hspb8 (heat shock protein 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspb8 (heat shock protein family B (small) member 8)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPB8 (heat shock protein family B (small) member 8)
Canis lupus familiaris (dog) : HSPB8 (heat shock protein family B (small) member 8)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965479 (uncharacterized LOC101965479)
Sus scrofa (pig) : HSPB8 (heat shock protein family B (small) member 8)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01245,905,371 - 45,920,014 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01247,717,762 - 47,731,883 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41241,407,166 - 41,421,565 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11241,270,553 - 41,284,952 (+)NCBI
Celera1241,813,553 - 41,828,157 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hspb8
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71003
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.