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Gene: Adcy5 (adenylate cyclase 5) Rattus norvegicus
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Symbol: Adcy5
Name: adenylate cyclase 5
Description: Exhibits calcium- and calmodulin-responsive adenylate cyclase activity. Involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; cAMP biosynthetic process; and response to morphine. Localizes to the endosome; membrane raft; and plasma membrane. Colocalizes with the sarcolemma. Biomarker of hypertension and type 2 diabetes mellitus. Orthologous to human ADCY5 (adenylate cyclase 5); PARTICIPATES IN G protein mediated signaling pathway via Galphas family; glucagon signaling pathway; dopamine signaling pathway via D1 family of receptors; INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 6-propyl-2-thiouracil; 7,12-dimethyltetraphene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adenylate cyclase type 5; adenylate cyclase type V; adenylyl cyclase 5; adenylyl cyclase type V; ATP pyrophosphate-lyase 5
Orthologs:
Homo sapiens (human) : ADCY5 (adenylate cyclase 5)  HGNC  Alliance
Mus musculus (house mouse) : Adcy5 (adenylate cyclase 5)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY5 (adenylate cyclase 5)
Canis lupus familiaris (dog) : ADCY5 (adenylate cyclase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy5 (adenylate cyclase 5)
Sus scrofa (pig) : ADCY5 (adenylate cyclase 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01168,695,839 - 68,842,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01171,787,104 - 71,933,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,290,968 - 67,437,468 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11167,348,556 - 67,495,057 (-)NCBI
Celera1164,930,432 - 65,076,790 (-)NCBICelera
Cytogenetic Map11q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Adcy5
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71014
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.