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Gene: Lman1 (lectin, mannose-binding, 1) Rattus norvegicus
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Symbol: Lman1
Name: lectin, mannose-binding, 1
Description: Exhibits identical protein binding activity. Predicted to be involved in several processes, including Golgi organization; endoplasmic reticulum organization; and endoplasmic reticulum to Golgi vesicle-mediated transport. Localizes to the cytoplasm and integral component of membrane. Human ortholog(s) of this gene implicated in factor V deficiency and factor XIII deficiency. Orthologous to human LMAN1 (lectin, mannose binding 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; protein secretory pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 2-methoxyethanol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: endoplasmic reticulum-golgi intermediate compartment protein 53; ER-Golgi intermediate compartment 53 kDa protein; lectin mannose-binding 1; p58; protein ERGIC-53
Orthologs:
Homo sapiens (human) : LMAN1 (lectin, mannose binding 1)  HGNC  Alliance
Mus musculus (house mouse) : Lman1 (lectin, mannose-binding, 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Lman1 (lectin, mannose binding 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LMAN1 (lectin, mannose binding 1)
Canis lupus familiaris (dog) : LMAN1 (lectin, mannose binding 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Lman1 (lectin, mannose binding 1)
Sus scrofa (pig) : LMAN1 (lectin, mannose binding 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01861,683,377 - 61,707,344 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01860,880,943 - 60,901,877 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41862,504,296 - 62,524,151 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11862,577,496 - 62,597,352 (+)NCBI
Celera1857,631,372 - 57,651,369 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Lman1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71020
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.