Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Itga7 (integrin subunit alpha 7) Rattus norvegicus
Analyze
Symbol: Itga7
Name: integrin subunit alpha 7
Description: Exhibits integrin binding activity; laminin binding activity; and protein heterodimerization activity. Involved in cell adhesion; integrin-mediated signaling pathway; and skeletal muscle tissue development. Localizes to the cell surface and integrin complex. Used to study cardiomyopathy. Biomarker of arteriosclerosis. Human ortholog(s) of this gene implicated in Duchenne muscular dystrophy; congenital muscular dystrophy due to integrin alpha-7 deficiency; and muscular disease. Orthologous to human ITGA7 (integrin subunit alpha 7); PARTICIPATES IN integrin mediated signaling pathway; altered integrin mediated signaling pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: alpha 7A integrin; H36-alpha7; integrin alpha 7; integrin alpha-7; integrin, alpha 7; MGC105724
Orthologs:
Homo sapiens (human) : ITGA7 (integrin subunit alpha 7)  HGNC  Alliance
Mus musculus (house mouse) : Itga7 (integrin alpha 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itga7 (integrin subunit alpha 7)
Pan paniscus (bonobo/pygmy chimpanzee) : ITGA7 (integrin subunit alpha 7)
Canis lupus familiaris (dog) : ITGA7 (integrin subunit alpha 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itga7 (integrin subunit alpha 7)
Sus scrofa (pig) : ITGA7 (integrin subunit alpha 7)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.073,355,079 - 3,383,886 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.073,325,268 - 3,354,361 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.472,230,747 - 2,269,403 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.172,230,888 - 2,269,401 (+)NCBI
Celera71,231,167 - 1,259,461 (+)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Itga7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71022
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.