Gene: Actr3 (actin related protein 3) Rattus norvegicus
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Symbol: Actr3
Name: actin related protein 3
Description: Exhibits ATPase binding activity and actin binding activity; predicted to contribute to actin filament binding activity; involved in several processes, including cellular response to cytokine stimulus, nervous system development, and positive regulation of cellular component organization; localizes to several cellular components, including the apical ectoplasmic specialization, apical tubulobulbar complex, and cytoplasm; colocalizes with the actin filament; used to study focal segmental glomerulosclerosis; biomarker of focal segmental glomerulosclerosis and schizophrenia; orthologous to human ACTR3 (actin related protein 3); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; platelet-derived growth factor signaling pathway; INTERACTS WITH 2,4-dibromophenyl 2,4,5-tribromophenyl ether; 2,4-dinitrotoluene; 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: actin-like protein 3; actin-related protein 3; actin-related protein 3 homolog (yeast); actin-related protein 3 homolog (yest); Arp3; ARP3 actin related protein 3 homolog; ARP3 actin-related protein 3 homolog; ARP3 actin-related protein 3 homolog (yeast); MGC116163
Orthologs:
Homo sapiens (human) : ACTR3 (actin related protein 3)  HGNC  Alliance
Mus musculus (house mouse) : Actr3 (ARP3 actin-related protein 3)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Actr3 (actin related protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ACTR3 (actin related protein 3)
Canis lupus familiaris (dog) : ACTR3 (actin related protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Actr3 (actin related protein 3)
Sus scrofa (pig) : ACTR3 (actin related protein 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01341,695,520 - 41,738,622 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01346,808,187 - 46,850,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41337,861,558 - 37,904,589 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11337,876,286 - 37,879,398 (-)NCBI
Celera1336,607,886 - 36,650,420 (-)NCBICelera
Cytogenetic Map13q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Actr3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71024
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.