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Gene: Col3a1 (collagen type III alpha 1 chain) Rattus norvegicus
Symbol: Col3a1
Name: collagen type III alpha 1 chain
Description: Predicted to have several functions, including integrin binding activity; platelet-derived growth factor binding activity; and protease binding activity. Involved in response to mechanical stimulus and skeletal system development. Localizes to collagen-containing extracellular matrix. Biomarker of bladder neck obstruction; glomerulosclerosis; myocardial infarction; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome; autosomal dominant type IV Ehlers-Danlos syndrome; end stage renal failure; and type III Ehlers-Danlos syndrome. Orthologous to human COL3A1 (collagen type III alpha 1 chain); PARTICIPATES IN cell-extracellular matrix signaling pathway; Entamoebiasis pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-noradrenaline; 1-naphthyl isothiocyanate.
Type: protein-coding
Also known as: collagen alpha-1(III) chain; collagen, type III, alpha 1; MGC93704; procollagen type III alpha 1; procollagen, type III, alpha 1
Homo sapiens (human) : COL3A1 (collagen type III alpha 1 chain)  HGNC  Alliance
Mus musculus (house mouse) : Col3a1 (collagen, type III, alpha 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col3a1 (collagen type III alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL3A1 (collagen type III alpha 1 chain)
Canis lupus familiaris (dog) : COL3A1 (collagen type III alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col3a1 (collagen type III alpha 1 chain)
Sus scrofa (pig) : COL3A1 (collagen type III alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL3A1 (collagen type III alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col3a1 (collagen type III alpha 1 chain)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0952,023,295 - 52,059,221 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl952,023,295 - 52,059,217 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0951,689,492 - 51,725,418 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4944,281,582 - 44,317,831 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1944,310,161 - 44,319,243 (+)NCBI
Celera945,061,755 - 45,097,754 (+)NCBICelera
Cytogenetic Map9q22NCBI
RH 3.4 Map9388.09RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Col3a1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71029
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-03-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.