Gene: Htr7 (5-hydroxytryptamine receptor 7) Rattus norvegicus
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Symbol: Htr7
Name: 5-hydroxytryptamine receptor 7
Description: Exhibits G protein-coupled serotonin receptor activity; involved in several processes, including adenylate cyclase-activating serotonin receptor signaling pathway, generation of neurons, and modulation of chemical synaptic transmission; localizes to several cellular components, including the cytoplasm, intrinsic component of plasma membrane, and neuron projection; used to study amnestic disorder, anxiety disorder, childhood absence epilepsy, cognitive disorder, and migraine; biomarker of irritable bowel syndrome; orthologous to human HTR7 (5-hydroxytryptamine receptor 7); PARTICIPATES IN serotonin signaling pathway via receptors engaging G alphas protein family; calcium/calcium-mediated signaling pathway; INTERACTS WITH (RS)-amphetamine; 6-propyl-2-thiouracil; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 5-HT-7; 5-HT-X; 5-HT7; 5-hydroxytryptamine (serotonin) receptor 7; 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled; 5Ht7; GPRFO; high affinity serotonin receptor (5HT7); high affinity serotonin receptor (5HT7) gene; serotonin receptor 7
Orthologs:
Homo sapiens (human) : HTR7 (5-hydroxytryptamine receptor 7)  HGNC  Alliance
Mus musculus (house mouse) : Htr7 (5-hydroxytryptamine (serotonin) receptor 7)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Htr7 (5-hydroxytryptamine receptor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : HTR7 (5-hydroxytryptamine receptor 7)
Canis lupus familiaris (dog) : HTR7 (5-hydroxytryptamine receptor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Htr7 (5-hydroxytryptamine receptor 7)
Sus scrofa (pig) : HTR7 (5-hydroxytryptamine receptor 7)
more info ...
Is Marker For: Strains:   WI-Htr7em1Geh  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01254,547,964 - 254,671,811 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01261,759,122 - 261,879,914 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41240,136,279 - 240,260,620 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11240,308,574 - 240,434,503 (-)NCBI
Celera1230,737,463 - 230,859,847 (-)NCBICelera
Cytogenetic Map1q53NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Htr7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71034
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.