Gene: Cdc42 (cell division cycle 42) Rattus norvegicus
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Symbol: Cdc42
Name: cell division cycle 42
Description: Exhibits GTP binding activity and mitogen-activated protein kinase kinase kinase binding activity; involved in several processes, including Cdc42 protein signal transduction, positive regulation of cellular metabolic process, and regulation of synapse organization; localizes to the Schaffer collateral - CA1 synapse, cytoplasm, and plasma membrane; predicted to colocalize with the centrosome; biomarker of temporal lobe epilepsy; orthologous to human CDC42 (cell division cycle 42); PARTICIPATES IN Rho/Rac/Cdc42 mediated signaling pathway; adenosine signaling pathway; c-Jun N-terminal kinases MAPK signaling pathway; INTERACTS WITH 2,4-dinitrotoluene; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cell division control protein 42 homolog; cell division cycle 42 (GTP binding protein); cell division cycle 42 homolog; cell division cycle 42 homolog (S. cerevisiae)
Orthologs:
Homo sapiens (human) : CDC42 (cell division cycle 42)  HGNC  Alliance
Mus musculus (house mouse) : Cdc42 (cell division cycle 42)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc42 (cell division cycle 42)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC42 (cell division cycle 42)
Canis lupus familiaris (dog) : CDC42 (cell division cycle 42)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc42 (cell division cycle 42)
Sus scrofa (pig) : CDC42 (cell division cycle 42)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05155,690,267 - 155,728,385 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05159,446,154 - 159,485,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45156,106,123 - 156,143,040 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15156,116,164 - 156,153,079 (-)NCBI
Celera5147,953,334 - 147,989,998 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cdc42
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71043
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.