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Gene: Ap2b1 (adaptor related protein complex 2 subunit beta 1) Rattus norvegicus
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Symbol: Ap2b1
Name: adaptor related protein complex 2 subunit beta 1
Description: Exhibits clathrin binding activity. Involved in several processes, including clathrin coat assembly; negative regulation of neuron death; and positive regulation of endocytosis. Localizes to the clathrin coat. Biomarker of middle cerebral artery infarction. Orthologous to human AP2B1 (adaptor related protein complex 2 subunit beta 1); PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; endocytosis pathway; Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: adapter-related protein complex 2 beta subunit; adapter-related protein complex 2 subunit beta; adaptor protein complex AP-2 subunit beta; adaptor-related protein complex 2 subunit beta; adaptor-related protein complex 2, beta 1 subunit; AP-1 complex subunit beta-1-like; AP-2 complex subunit beta; AP105B; beta adaptin; beta-2-adaptin; beta-adaptin; beta2-adaptin; clathrin assembly protein complex 2 beta large chain; LOC100912146; plasma membrane adaptor HA2/AP2 adaptin beta subunit
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01070,516,462 - 70,621,973 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01071,068,935 - 71,083,997 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01071,035,406 - 71,067,828 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41071,386,233 - 71,488,000 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11071,399,684 - 71,502,555 (+)NCBI
Celera1067,045,800 - 67,146,677 (+)NCBICelera
Cytogenetic Map10q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Ap2b1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71048
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.