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Gene: Cilk1 (ciliogenesis associated kinase 1) Rattus norvegicus
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Symbol: Cilk1
Name: ciliogenesis associated kinase 1
Description: Exhibits ATP binding activity and protein serine/threonine kinase activity. Involved in intracellular signal transduction and protein phosphorylation. Localizes to cytoplasm. Human ortholog(s) of this gene implicated in endocrine-cerebro-osteodysplasia syndrome and juvenile myoclonic epilepsy 10. Orthologous to human CILK1 (ciliogenesis associated kinase 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: heart serine-threonine protein kinase; Ick; intestinal cell (MAK-like) kinase; intestinal cell kinase; MAK-related kinase; MRK; serine/threonine-protein kinase ICK
Orthologs:
Homo sapiens (human) : CILK1 (ciliogenesis associated kinase 1)  HGNC  Alliance
Mus musculus (house mouse) : Cilk1 (ciliogenesis associated kinase 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cilk1 (ciliogenesis associated kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CILK1 (ciliogenesis associated kinase 1)
Canis lupus familiaris (dog) : CILK1 (ciliogenesis associated kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cilk1 (ciliogenesis associated kinase 1)
Sus scrofa (pig) : CILK1 (ciliogenesis associated kinase 1)
Chlorocebus sabaeus (African green monkey) : CILK1 (ciliogenesis associated kinase 1)
Heterocephalus glaber (naked mole-rat) : Cilk1 (ciliogenesis associated kinase 1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0885,413,998 - 85,473,374 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl885,413,537 - 85,472,694 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0884,982,701 - 85,037,684 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4883,086,346 - 83,140,977 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1883,105,399 - 83,160,031 (+)NCBI
Celera878,732,894 - 78,787,000 (+)NCBICelera
Cytogenetic Map8q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Cilk1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71050
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.