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Gene: Hnrnpl (heterogeneous nuclear ribonucleoprotein L) Rattus norvegicus
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Symbol: Hnrnpl
Name: heterogeneous nuclear ribonucleoprotein L
CRRD ID: 71059
Description: Exhibits mRNA 3'-UTR binding activity and mRNA CDS binding activity. Involved in several processes, including cellular response to amino acid starvation; positive regulation of mRNA binding activity; and regulation of gene expression. Localizes to cytosol; nucleus; and perinuclear region of cytoplasm. Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and systemic scleroderma. Orthologous to human HNRNPL (heterogeneous nuclear ribonucleoprotein L); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: heterogenous nuclear ribonucleoprotein L; hnrnp-L; Hnrpl
Orthologs:
Homo sapiens (human) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)  HGNC  Alliance
Mus musculus (house mouse) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
Pan paniscus (bonobo/pygmy chimpanzee) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Canis lupus familiaris (dog) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
Sus scrofa (pig) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Chlorocebus sabaeus (African green monkey) : HNRNPL (heterogeneous nuclear ribonucleoprotein L)
Heterocephalus glaber (naked mole-rat) : Hnrnpl (heterogeneous nuclear ribonucleoprotein L)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0186,994,090 - 87,006,776 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl186,996,093 - 87,006,776 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0188,174,400 - 88,187,394 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4183,919,015 - 83,929,698 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1184,005,781 - 84,007,795 (+)NCBI
Celera178,491,204 - 78,501,887 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Hnrnpl
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

CRRD Object Information
CRRD ID: 71059
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.